Ubuntu works pretty well on this machine with the exception of Suspend and Resume being broken.

These tutorials helped me sort that out:
http://thecodecentral.com/2011/01/18/fix-ubuntu-10-10-suspendhibernate-not-working-bug
http://askubuntu.com/questions/67280/wireless-doesnt-connect-after-suspend-on-an-asus-k52f

Firstly unbind/bind problematic drivers on suspend/resume

Create an executable file here:

/etc/pm/sleep.d/20_custom-ehci_hcd

Containing this:

#!/bin/sh
#inspired by http://art.ubuntuforums.org/showpost.php?p=9744970&postcount=19
#...and http://thecodecentral.com/2011/01/18/fix-ubuntu-10-10-suspendhibernate-not-working-bug    
# tidied by tqzzaa :)

VERSION=1.1
DEV_LIST=/tmp/usb-dev-list
DRIVERS_DIR=/sys/bus/pci/drivers
DRIVERS="ehci xhci" # ehci_hcd, xhci_hcd
HEX="[[:xdigit:]]"
MAX_BIND_ATTEMPTS=2
BIND_WAIT=0.1

unbindDev() {
  echo -n > $DEV_LIST 2>/dev/null
  for driver in $DRIVERS; do
    DDIR=$DRIVERS_DIR/${driver}_hcd
    for dev in `ls $DDIR 2>/dev/null | egrep "^$HEX+:$HEX+:$HEX"`; do
      echo -n "$dev" > $DDIR/unbind
      echo "$driver $dev" >> $DEV_LIST
    done
  done
}

bindDev() {
  if [ -s $DEV_LIST ]; then
    while read driver dev; do
      DDIR=$DRIVERS_DIR/${driver}_hcd
      while [ $((MAX_BIND_ATTEMPTS)) -gt 0 ]; do
          echo -n "$dev" > $DDIR/bind
          if [ ! -L "$DDIR/$dev" ]; then
            sleep $BIND_WAIT
          else
            break
          fi
          MAX_BIND_ATTEMPTS=$((MAX_BIND_ATTEMPTS-1))
      done  
    done < $DEV_LIST
  fi
  rm $DEV_LIST 2>/dev/null
}

case "$1" in
  hibernate|suspend) unbindDev;;
  resume|thaw)       bindDev;;
esac

And then unload/load WiFi drivers on suspend/resume

Create an executable file here:

/etc/pm/sleep.d/00_wireless_sleep

And fill it with this:

#!/bin/sh

case "$1" in
  suspend|hibernate)
  /sbin/rmmod ath9k
  ;;
  resume|thaw)
  /sbin/rmmod ath9k
  /sbin/modprobe ath9k 
  ;;
esac
exit 0